Evaluación de la función del eje hipotálamo-hipófisis-adrenal en niños tratados con esteroides

  • Alejandra Vélez Palacio Universidad de Antioquia
  • Vital Balthazar González Universidad de Antioquia
  • Germán Campuzano Maya Laboratorio Clínico Hematológico
Palabras clave: insuficiencia suprarrenal, esteroides, hidrocortisona, hormona adrenocorticotrópica, sistema hipófiso-suprarrenal.

Resumen

El uso frecuente de medicamentos esteroideos constituye un riesgo de supresión del eje hipotálamo-hipófisis-adrenal, en particular si el tratamiento se usa por más de cuatro semanas. El retiro planeado del medicamento y la evaluación oportuna mediante la prueba corta de estimulación con hormona adrenocorticotrópica permiten identificar los niños en riesgo de presentar una crisis o una insuficiencia adrenal, como también establecer la necesidad de suplementar a los pacientes con esteroides durante situaciones de estrés. En este artículo de revisión se describen los efectos de los esteroides sobre el eje hipotálamo-hipófisis-adrenal en pacientes pediátricos, los esquemas de retiro gradual de los esteroides y las pruebas para evaluar la función del eje hipotálamo-hipófisis-adrenal en dichos pacientes.

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Biografía del autor/a

Alejandra Vélez Palacio, Universidad de Antioquia

Médica Pediatra. Residente de endocrinología pediátrica, Universidad de Antioquia. Medellín, Colombia.

Vital Balthazar González , Universidad de Antioquia

Médico Pediatra Endocrinólogo. Docente del Departamento de Pediatría de la Facultad de Medicina, Universidad de Antioquia. Medellín, Colombia.

Germán Campuzano Maya , Laboratorio Clínico Hematológico

Médico especialista en Hematología y Patología Clínica. Docente, Ad Honorem, Facultad de Medicina, Universidad de Antioquia. Médico Director, Laboratorio Clínico Hematológico. Medellín, Colombia.

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Cómo citar
1.
Vélez Palacio A, Balthazar González V, Campuzano Maya G. Evaluación de la función del eje hipotálamo-hipófisis-adrenal en niños tratados con esteroides. Med. Lab. [Internet]. 1 de marzo de 2013 [citado 2 de junio de 2020];19(3-4):111-25. Disponible en: https://medicinaylaboratorio.com/index.php/myl/article/view/218
Publicado
2013-03-01
Sección
La Clínica y el Laboratorio