Deficiencia de andrógenos y enfermedad cardiovascular en el hombre

  • Andrés Federico Botero-Arango Universidad CES
  • Mauricio Duque-Ramírez Universidad CES
  • Laura Duque-González Universidad CES
Palabras clave: testosterona, hipogonadismo, globulina de unión a hormona sexual, terapia de reemplazo de hormonas.

Resumen

El hipogonadismo masculino, manifestado por la disminución de los niveles séricos de testosterona, representa una causa importante de morbimortalidad en pacientes mayores de 40 años. Su prevalencia es proporcional a la edad, y las diversas manifestaciones clínicas, de índole física, sicológica y sexual, conllevan a un marcado deterioro clínico del paciente. El impacto de la deficiencia de testosterona sobre el aparato cardiovascular acelera la progresión de la enfermedad coronaria, disminuye la sensibilidad a la insulina y aumenta la mortalidad global. Según la Sociedad Americana de Endocrinología, el diagnóstico bioquímico se realiza con valores de testosterona total <300 mg/dL. Definir el inicio de la terapia de reemplazo con testosterona siempre deberá incluir la clínica y las mediciones de laboratorio. El efecto sistémico de la terapia se verá reflejado en la mejoría de la fatiga, de la libido y del mejor control de los factores de riesgo cardiovascular, que incluye la disminución de la grasa visceral, mejoría de la sensibilidad a la insulina, del perfil lipídico, de las cifras de presión arterial y en algunos casos, disminución de la mortalidad.

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Biografía del autor/a

Andrés Federico Botero-Arango, Universidad CES

Médico especialista en medicina interna, especialista en cardiología y fellow de electrofisiología, Universidad CES.

Mauricio Duque-Ramírez, Universidad CES

Médico especialista en medicina interna, cardiología y electrofisiología. Profesor titular de cardiología y electrofisiología Universidad CES. Jefe del servicio de cardiología y electrofisiología, Universidad CES.

Laura Duque-González, Universidad CES

Estudiante de Medicina, Universidad CES.

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Cómo citar
1.
Botero-Arango AF, Duque-Ramírez M, Duque-González L. Deficiencia de andrógenos y enfermedad cardiovascular en el hombre. Med. Lab. [Internet]. 1 de enero de 2014 [citado 25 de octubre de 2021];20(1-2):43-6. Disponible en: https://medicinaylaboratorio.com/index.php/myl/article/view/156
Publicado
2014-01-01
Sección
Endocrinología

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