Diagnóstico micológico: de los métodos convencionales a los moleculares

  • Verónica J. Tangarife-Castaño Editora Médica Colombiana
  • Sindy V. Flórez-Muñoz Universidad de Antioquia
  • Ana C. Mesa-Arango Universidad de Antioquia
Palabras clave: micosis, técnicas de laboratorio clínico, técnicas de diagnóstico molecular, epidemiología.

Resumen

La incidencia de las infecciones fúngicas ha aumentado en las últimas décadas como consecuencia del incremento en el número de pacientes con factores predisponentes. Tanto el diagnóstico como el tratamiento de estas infecciones continúan siendo un reto para el personal de la salud. Aunque las especies de los géneros Candida, Aspergillus y Cryptococcus continúan siendo las más frecuentes, es notoria la emergencia de especies que no se habían reconocido anteriormente como patógenas para el hombre. Ante este panorama, el diagnóstico adecuado y oportuno de estas infecciones es de gran relevancia para la instauración de un tratamiento eficaz y, de esta manera, para impactar en la morbilidad y mortalidad que suelen causar algunas micosis, principalmente en los individuos inmunocomprometidos. Con esta revisión se pretende mostrar de manera general aspectos clínicos, epidemiológicos y, principalmente, relacionados con el diagnóstico de las infecciones fúngicas más frecuentes, partiendo de los métodos convencionales hasta las técnicas moleculares que actualmente se tratan de implementar en busca de un la prueba estándar de referencia que pueda superar la sensibilidad, la especificidad, la rapidez y el costo-efectividad de los métodos que se han utilizado hasta ahora en el diagnostico micológico.

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Biografía del autor/a

Verónica J. Tangarife-Castaño, Editora Médica Colombiana

Microbióloga y Bioanalista. Candidata a MSc en Ciencias Básicas Biomédicas, Universidad de Antioquia. Estudiante de maestría, Grupo de Investigación Dermatológica (GRID), Universidad de Antioquia. Coordinadora Científica, Editora Médica Colombiana S.A. Medellín, Colombia.

Sindy V. Flórez-Muñoz, Universidad de Antioquia

Estudiante de Biología, Universidad de Antioquia. Grupo de Investigación Dermatológica (GRID), Universidad de Antioquia. Medellín, Colombia.

Ana C. Mesa-Arango, Universidad de Antioquia

Bacterióloga y laboratorista clínica, especialista en Micología Médica, MSc en Biología Experimental, PhD en Microbiología y Parasitología. Docente, Facultad de Medicina, Universidad de Antioquia. Grupo de Investigación Dermatológica (GRID), Universidad de Antioquia. Medellín, Colombia.

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Cómo citar
1.
Tangarife-Castaño VJ, Flórez-Muñoz SV, Mesa-Arango AC. Diagnóstico micológico: de los métodos convencionales a los moleculares. Med. Lab. [Internet]. 1 de mayo de 2015 [citado 26 de enero de 2021];21(5-6):211-42. Disponible en: https://medicinaylaboratorio.com/index.php/myl/article/view/121
Publicado
2015-05-01
Sección
La Clínica y el Laboratorio